技术平台
TECHNOLOGY PLATFORM
Highly Potent Small-molecule Candidates
with Accelerated and Cost-efficient Discovery
Small-molecule Degrader
Oral Molecular Glue/PROTAC Discovery
◆ AI-driven Modeling & Virtual Screening
◆ Structure-guided Rational Design
◆ High-throughput Proteomic Screening
◆ Novel Target & E3 Ligand identification
◆ Proximity-based Assay Validation
PRODEGRE ATLAS™ : 创新蛋白降解与互作平台
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Translational Medicine
转化医学
Prodegre is strategically building a comprehensive AI agent ecosystem to power multiple AI co-scientists
• An AI co-scientist platform that unifies hypothesis generation, reasoning, and experimental feedback to accelerate discovery, improve efficiency and reduce labour costs.
• Explore hypothesis space and generate testable biological hypotheses beyond human-scale search.
• Agents leverage structured memory and feedback to continuously learn, update knowledge, and reduce uncertainty in decision-making.
01
AI co-scientist
AI agent ecosystem
In-house proprietary algorithms enabling systematic discovery of novel degrons
• β-hairpin G-loop & non-canonical motif discovery
• Molecular surface mimicry
• Novel E3 ligase degron motif discovery
• Integrated computational and experimental approaches
02
Degron Discovery
Proprietary algorithms development
03
Structure-guided Discovery
AI-driven ternary complex modeling and prediction
Prodegre leverages AI-driven structure-based prediction to power rational design of degraders
• High-quality structural ensembles
• Productive ubiquitination configurations
• Complex stability and residence time
• Prediction of BBB permeability
• DMPK Optimization under ternary complex constraints
AI-Driven Discovery Platform
AI驱动的探索平台
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